Fluorometric probing of the lipase level as acute pancreatitis biomarkers based on interfacially controlled aggregation-induced emission (AIE)† †Electronic supplementary information (ESI) available: Synthesis, characterisation, test conditions and other supplementary data. See DOI: 10.1039/c7sc02189e Click here for additional data file.

Fluorometric probing of the lipase level as acute pancreatitis biomarkers based on interfacially controlled aggregation-induced emission (AIE).

As a sudden inflammation of the pancreas, acute pancreatitis presents severe complications and a high mortality rate, despite treatment. Lipase in serum serves as an essential biomarker of acute pancreatitis and even pancreatic cancer. Therefore, developing robust, convenient and sensitive probing of lipase levels is greatly needed. In this work, we present glutamate functionalized tetraphenyle...

Tuning the singlet-triplet energy gap: a unique approach to efficient photosensitizers with aggregation-induced emission (AIE) characteristics† †Electronic supplementary information (ESI) available: Synthesis and characterization of the intermediates and molecular orbital data. See DOI: 10.1039/c5sc01733e Click here for additional data file.

Pd-η 3-C6H9 complexes of the Trost modular ligand: high nuclearity columnar aggregation controlled by concentration, solvent and counterion† †Electronic supplementary information (ESI) available: Synthesis and Characterisation of compounds, and full details of aggregation studies by NMR, SANS, and MM3. See DOI: 10.1039/c5sc01181g Click here for additional data file.

pH controlled assembly of a self-complementary halogen-bonded dimer† †Electronic supplementary information (ESI) available: Details of computational methods, synthesis and characterisation data for all compounds are provided. CCDC 1488032–1488035. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc03696a Click here for additional data file. Click here for additional data file.

Enantioselective Narasaka–Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters† †Electronic supplementary information (ESI) available: Experimental procedures and characterisation data for all compounds are provided. CCDC 1438659 and 1438660. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc04466b Click here for additional data file. Click here for additional data file.

School of Chemistry, University of Bristol, B bris.ac.uk AstraZeneca, Alderley Park, Maccleseld, C AstraZeneca, Pepparedsleden 1, Mölndal, 4 † Electronic supplementary information ( and characterisation data for all compou 1438660. For ESI and crystallographic dat DOI: 10.1039/c6sc04466b ‡ These authors contributed equally. § Author to whom correspondence shou structures of 3b and Pd[(Sa,S)-L-...